Publications by CharlestonPharma employees

1Sengupta TK, Bandyopadhyay S, Fernandes DJ, Spicer EK. Identification of nucleolin as an AU-rich element binding protein involved in bcl-2 mRNA stabilization. J Biol Chem. 2004; 279:10855-63.

2Otake Y, Sengupta TK, Bandyopadhyay S, Spicer EK, and Fernandes DJ: Retinoid-Induced Apoptosis in HL-60 Cells is associated with nucleolin downregulation and destabilization of Bcl-2 mRNA. Mol. Pharmacol. 2005; 67:319-326.

3Otake Y, Soundararajan S, Sengupta TK, Kio EA, Smith JC, Pineda-Roman M, et al. Overexpression of nucleolin in chronic lymphocytic leukemia cells induces stabilization of bcl2 mRNA.Blood. 2007; 109:30693075.

4Soundararajan S, Chen W, Spicer EK, Courtenay-Luck N, Fernandes DJ. The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cells. Cancer Res. 2008; 68:2358-65.

5Gattoni-Celli S, Buckner C.L,. Lazarchick, Stuart, R.K., and Fernandes, D.J.. Overexpression of Nucleolin in Engrafted Acute Myelogenous Leukemia (AML) Cells. Am. J of Hematology. 2009; 84:535-537,2009

6Soundararajan S, Wang L, Sridharan V, Chen W, Courtenay-Luck N, Jones D, et al. Plasma Membrane Nucleolin is a Receptor for the Anticancer Aptamer AS1411 in MV4-11 Leukemia Cells. Mol Pharmacol. 2009; 76:1-8.

7Ishimaru D, Zuraw L, Ramalingam S, Sengupta TK, Bandyopadhyay S, Reuben A, Fernandes DJ, Spicer EK: Mechanism of regulation of Bcl-2 mRNA by nucleolin and A+U rich element biding factor 1 (AUF1). J Biol Chem. 2010; 285:27182-27191.

8Daniel J. Fernandes, Yoko Otake, and Robert L. Capizzi. Human anti-nucleolin antibodies with broad spectrum anticancer activity. Cancer Res. 2012; 72 (8 Supplement): 4623.

Key publications by others

9Deng J-S, Ballou B. Hoffmeister JK. Internalization of anti-nucleolin antibody into viable HEp-2 cells. Molecular Biology Reports. 23:1996:191-195

10Hovanessian AG, Puvion-Dutilleul F, Nisole S, Svab J, Perret E, Deng JS, Krust B. Cell-surface-expressed nucleolin is associated with the actin cytoskeleton. Exp Cell Res 2000; 261:312-328.

11Fogal V, Sugahara KN, Ruoslahti E, Christian S. Cell surface nucleolin antagonist causes endothelial cell apoptosis and normalization of tumor vasculature. Angiogenesis 2009; 12:91-100.

12Hovanessian AG, Soundaramourty C, Khoury DE, Nondier I, Svab J, Krust B. Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization. PLoS ONE 2010; 5:e15787.

13Watanabe T, Hirano K, Takahashi A, Yamaguchi K, Beppu M, Fujiki H, Suganuma M. Nucleolin on the cell surface as a new molecular target for gastric cancer treatment. Biol Pharm Bull 2010; 33:796-803.

14Abdelmohsen K and Gorospe M. RNA binding protein nucleolin in disease. RNA Biology 2012; 96:799-808.